Computational biophysics

A coarse-grained model enables simulating droplet formation with low-complexity RNA sequences.

Plasmodium sporozoites can move in rotating vortices owing to their chiral shape and mechanical flexibility, revealing important physical aspects of collective motion.

Individual cilia are typically attached to cell surfaces, where they sweep back and forth. A new study charts the behavioural space of the beating patterns of cilia isolated from the cell.

AlphaFold is a neural-network-based approach to predicting protein structures with high accuracy. We describe how it works in general terms and discuss some anticipated impacts on the field of structural biology.