Reactive precursors

Reactive precursors are substances that exist as intermediates in multi-step reaction processes, such as in the synthesis of complex nanoparticles.

Latest Research and Reviews

News and Comment

  • News & Views |

    Methods for the synthesis of bicyclo[1.1.1]pentanes (BCPs) typically rely on the release of strain energy, but these routes cannot easily introduce substituents on the BCP bridges. Now, an intramolecular coupling gives access to multi-substituted BCPs, through the synthesis of bridge-substituted bicycloalkyl boronic esters.

    • Cara E. Brocklehurst
    •  & Edward A. Anderson
    Nature Chemistry 13, 928-930
  • News & Views |

    Free radicals are notorious for unselective coupling reactions; however, the coupling of free radicals generated from acyl tellurides has now been shown to form C–C bonds with remarkable fidelity, which enables easy one-step assembly of densely oxygenated natural product motifs.

    • Wenhao Zhang
    •  & Ang Li
    Nature Chemistry 9, 198-199