Peptic ulcers

Peptic ulcers are formed after a breach of the mucosa of the oesophagus, stomach (gastric ulcers) or upper part of the intestine (duodenal ulcers) as a result of the acidic environment. They are associated with Helicobacter pylori infection and use of nonsteroidal anti-inflammatory drugs, such as aspirin.

Latest Research and Reviews

Research
08 December 2021 | Open Access

Incidence and characteristics of death from peptic ulcer among cancer patients in the United States
- Pengcheng Yang
- , Yongqiang Zheng
- & Xiaohua Hou
Scientific Reports 11, 23579
Research
06 April 2021 | Open Access

How peptic ulcer disease could potentially lead to the lifelong, debilitating effects of chronic fatigue syndrome: an insight
- Chien-Feng Kuo
- , Leiyu Shi
- & Shin-Yi Tsai
Scientific Reports 11, 7520
Research
19 February 2021 | Open Access

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.
- Yeda Wu
- , Graham K. Murray
- & Naomi R. Wray
Nature Communications 12, 1146
Research
04 February 2020 | Open Access

Reciprocal association between depression and peptic ulcers: Two longitudinal follow-up studies using a national sample cohort
- So Young Kim
- , Chanyang Min
- & Hyo Geun Choi
Scientific Reports 10, 1749
Research
12 November 2019 | Open Access

Mucoadhesive effect of Curcuma longa extract and curcumin decreases the ranitidine effect, but not bismuth subsalicylate on ethanol-induced ulcer model
- Alejandra Orona-Ortiz
- , Luis Medina-Torres
- & Andrés Navarrete
Scientific Reports 9, 16622
Research
18 June 2019 | Open Access

A Differential Approach to Form and Site of Peptic Ulcer
- Walter Rau
- , Christoph Hohaus
- & Eike Jessen
Scientific Reports 9, 8683

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News and Comment

News & Views | 06 December 2011

Prediction and prevention of peptic ulcer rebleeding

Algorithms can predict the risk of rebleeding and mortality in patients with upper gastrointestinal bleeding, but not the risk of rebleeding following endoscopic treatment in patients with ulcers. A recent meta-analysis has addressed this issue, and could facilitate the development of methods to predict rebleeding and endoscopic treatments to reduce rebleeding.
- Dennis M. Jensen
Nature Reviews Gastroenterology & Hepatology 9, 7-8
Research Highlights | 06 June 2011

Novel nanopowder spray shows promising results in humans for the treatment of acute peptic ulcer bleeding
- Rachel Thompson
Nature Reviews Gastroenterology & Hepatology 8, 300

All News & Comment

Peptic ulcers

Latest Research and Reviews

Incidence and characteristics of death from peptic ulcer among cancer patients in the United States

How peptic ulcer disease could potentially lead to the lifelong, debilitating effects of chronic fatigue syndrome: an insight

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Reciprocal association between depression and peptic ulcers: Two longitudinal follow-up studies using a national sample cohort

Mucoadhesive effect of Curcuma longa extract and curcumin decreases the ranitidine effect, but not bismuth subsalicylate on ethanol-induced ulcer model

A Differential Approach to Form and Site of Peptic Ulcer

News and Comment

Prediction and prevention of peptic ulcer rebleeding

Novel nanopowder spray shows promising results in humans for the treatment of acute peptic ulcer bleeding

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