Organic chemistry

Organic chemistry is the study of the synthesis, structure, reactivity and properties of the diverse group of chemical compounds primarily constructed of carbon. All life on earth is carbon-based, thus organic chemistry is also the basis of biochemistry. The ability to form compounds containing long chains of carbon atoms is the basis of polymer chemistry.

Featured

Latest Research and Reviews

News and Comment

  • News & Views |

    Methods for the synthesis of bicyclo[1.1.1]pentanes (BCPs) typically rely on the release of strain energy, but these routes cannot easily introduce substituents on the BCP bridges. Now, an intramolecular coupling gives access to multi-substituted BCPs, through the synthesis of bridge-substituted bicycloalkyl boronic esters.

    • Cara E. Brocklehurst
    •  & Edward A. Anderson
    Nature Chemistry 13, 928-930
  • Research Highlights |

    Homochiral porous cage-in-cage structures that self-assemble from lanthanide cations and chiral amino acid-derived ligands have been prepared and shown to be highly effective in enantioselective separations of small-molecule guests.

    • Peter W. Seavill
  • News & Views |

    Benzene rings are almost unbreakable in typical reaction conditions. Chemistry has now been developed that selectively breaks these rings open, highlighting their potential as building blocks for making open-chain molecules.

    • Mark R. Crimmin
    Nature 597, 33-34
  • News & Views |

    Carbon–carbon single bonds are generally among the least reactive chemical bonds. While olefin metathesis reactions are well established, direct metathesis of C–C single bonds is rare. Now, a C–C single bond metathesis reaction has been developed, forming cross-biaryl products from unstrained homo-biaryl compounds.

    • Michael M. Gilbert
    •  & Daniel J. Weix
    Nature Chemistry 13, 818-820