Nanomedicine

  • Article |

    Lateral-flow in vitro diagnostic assays based on fluorescent nanodiamonds, in which microwave-based spin manipulation is used to increase sensitivity, are demonstrated using the biotin–avidin model and by the single-copy detection of HIV-1 RNA.

    • Benjamin S. Miller
    • , Léonard Bezinge
    •  & Rachel A. McKendry
  • Letter |

    The development of a nanoparticle RNA vaccine is reported that preferentially targets dendritic cells after systemic administration, and is shown to provide durable interferon-α-dependent antigen-specific immunity in mouse tumour models; initial results in advanced melanoma patients indicate potential efficacy in humans.

    • Lena M. Kranz
    • , Mustafa Diken
    •  & Ugur Sahin