Microbiology is the study of microscopic organisms, such as bacteria, viruses, archaea, fungi and protozoa. This discipline includes fundamental research on the biochemistry, physiology, cell biology, ecology, evolution and clinical aspects of microorganisms, including the host response to these agents.


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    Incorporating one-carbon molecules into metabolic engineering has involved altering central metabolism, which must overcome metabolic regulation. Developing one-carbon metabolic pathways that are orthogonal to central metabolism offers a promising alternative for bioproduct synthesis. Here, Chou, Lee, Zhu et al. describe an orthogonal pathway that has the potential for bioproduct synthesis from one-carbon molecules and can be independent of central metabolism.

    • Steven W. Singer
    Nature Metabolism 3, 1286-1287