Live attenuated vaccines

Lung fibroblastic stromal cells support inflating memory CD8⁺ T cells after vaccination with an adenovirus vector through the creation of organized lymphoid structures that support the metabolic fitness of these expanded antigen-specific T cells.

Could the BCG vaccine be used to bridge the gap until a specific COVID-19 vaccine is developed? Luke O’Neill and Mihai Netea discuss the science behind this approach.

Several recent studies are expanding our options to prevent and treat Ebolavirus, including new vaccine candidates and short interfering RNAs that target the viral genome.