Infectious diseases

Infectious diseases also known as contagious diseases, transmissible diseases or communicable diseases are caused by pathogenic microorganisms that infect a host organism and can be spread, directly or indirectly, from one organism to another.

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News & Views | 27 May 2022

A breath of fresh macrophages ameliorates inflammation in the hypoxic lung
- Federico F. De Ponti
- & Charlotte L. Scott
Nature Immunology, 1-3
News & Views | 26 May 2022

Viral protein activates the NLRP1 inflammasome
- Ella Hartenian
- & Petr Broz
Nature Immunology, 1-2
News & Views | 03 May 2022

From the archive: the link between mosquitoes and disease, and Mount Vesuvius erupts

Nature 605, 38

Latest Research and Reviews

Research | 27 May 2022

Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19
- Rosanna Asselta
- , Elvezia Maria Paraboschi
- & Cecilia Garlanda
Nature Immunology, 1-3
Research | 27 May 2022

Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19
- Michael Hultström
- , Robert Frithiof
- & Oskar Eriksson
Nature Immunology, 1-4
Research
27 May 2022 | Open Access

A cross-sectional survey on attitudes of men who have sex with men towards anal self-examination for detection of anal syphilis
- Ei T. Aung
- , Christopher K. Fairley
- & Eric P. F. Chow
Scientific Reports 12, 8962
Research
27 May 2022 | Open Access

Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients
- Eko Setiawan
- , Mohd-Hafiz Abdul-Aziz
- & Jason A. Roberts
Scientific Reports 12, 8930
Research
27 May 2022 | Open Access

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as children with multisystem inflammatory syndrome.
- Juanjie Tang
- , Tanya Novak
- & Surender Khurana
Nature Communications 13, 2979
Research
27 May 2022 | Open Access

Immune parameters of HIV susceptibility in the female genital tract before and after penile-vaginal sex

Mohammadi et al. evaluate immune markers and cell types associated with HIV susceptibility in the female genital tract before and after penile-vaginal sex. The authors report that these immune parameters increase rapidly and transiently after sex, with condom use affecting some of the changes observed.
- Avid Mohammadi
- , Sareh Bagherichimeh
- & Rupert Kaul
Communications Medicine 2, 60

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News and Comment

Research Highlights | 27 May 2022

Adipocytes behaving like immune cells
- Nicholas J. Bernard
Nature Immunology, 1
Research Highlights | 27 May 2022

Influenza replication drives cardiac dysfunction

A new study demonstrates that direct infection of cardiomyocytes is required to induce the cardiovascular effects of influenza virus infection.
- Karina Huynh
Nature Reviews Cardiology, 1
News & Views | 27 May 2022

A breath of fresh macrophages ameliorates inflammation in the hypoxic lung

Hypoxia alters populations of monocytes and macrophages during acute respiratory distress syndrome leading to persistent inflammation, a process that can be reversed by therapeutic administration of CSF1.
- Federico F. De Ponti
- & Charlotte L. Scott
Nature Immunology, 1-3
News & Views | 26 May 2022

Viral protein activates the NLRP1 inflammasome

Inflammasomes function as immune-signaling platforms that assemble following pathogen detection. Direct binding of a viral protein to NLRP1 and the disruption of a previously unknown autoinhibitory NRLP1 complex drive the activation of the NLRP1 inflammasome independently of the proteasome.
- Ella Hartenian
- & Petr Broz
Nature Immunology, 1-2
Comments & Opinion
25 May 2022 | Open Access

Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism

‘Affinity escape’: Novel SARS-CoV-2 variants may escape immunity by raising the RBD-ACE2 affinity high enough to outcompete the avidity of neutralizing antibodies.
- Martin F. Bachmann
- , Mona O. Mohsen
- & Daniel E. Speiser
npj Vaccines 7, 56
Research Highlights | 24 May 2022

Gut commensals promote antiviral immunity via extracellular vesicles

A new study shows that gut bacteria can enhance antiviral responses through the secretion of bacterial microvesicles.
- Alexandra Flemming
Nature Reviews Immunology, 1

All News & Comment

Infectious diseases

Featured

A breath of fresh macrophages ameliorates inflammation in the hypoxic lung

Viral protein activates the NLRP1 inflammasome

From the archive: the link between mosquitoes and disease, and Mount Vesuvius erupts

Latest Research and Reviews

Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19

Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

A cross-sectional survey on attitudes of men who have sex with men towards anal self-examination for detection of anal syphilis

Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

Immune parameters of HIV susceptibility in the female genital tract before and after penile-vaginal sex

News and Comment

Adipocytes behaving like immune cells

Influenza replication drives cardiac dysfunction

A breath of fresh macrophages ameliorates inflammation in the hypoxic lung

Viral protein activates the NLRP1 inflammasome

Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism

Gut commensals promote antiviral immunity via extracellular vesicles

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