Infectious diseases

  • Letter |

    The in vivo optical detection of bacterial infections requires highly specific imaging probes with small affinity to mammalian tissue. It is now shown that fluorescent dyes that are conjugated to maltohexaose can be internalized rapidly via the bacteria-specific maltodextrin transport pathway, enabling the in vivo imaging of Escherichia coli down to 105 colony-forming units.

    • Xinghai Ning
    • , Seungjun Lee
    •  & Niren Murthy