Immunology

Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms.

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News & Views | 10 August 2022

Immune cells use hunger hormones to aid healing
- Vishwa Deep Dixit
Nature
News & Views | 10 August 2022

Neurons shape the identity of microglia in the brain

Nature
News & Views | 04 August 2022

Inflammatory platelet death drives sepsis
- Luke Brown
- & Bryan G. Yipp
Nature Cardiovascular Research, 1-2

Latest Research and Reviews

Research | 10 August 2022

A monocyte–leptin–angiogenesis pathway critical for repair post-infection

Monocytes recruited to skin infection are not involved in bacterial clearance but instead regulate local angiogenesis and healing.
- Rachel M. Kratofil
- , Hanjoo B. Shim
- & Paul Kubes
Nature, 1-8
Research | 10 August 2022

The cross-talk of cancer-associated fibroblasts assist in prognosis and immunotherapy in patients with breast carcinoma
- Xuyu Gu
- , Shiya Zheng
- & Qin Zhou
Cancer Gene Therapy, 1-12
Research
10 August 2022 | Open Access

Diverse mutational landscapes in human lymphocytes

Sequencing of individual human lymphocyte clones shows that they are highly prone to mutations, with higher burdens in memory cells than in naive cells arising from mutational processes associated with differentiation and tissue residency.
- Heather E. Machado
- , Emily Mitchell
- & Peter J. Campbell
Nature, 1-9
Research
10 August 2022 | Open Access

Molecular basis of MHC I quality control in the peptide loading complex

The immune system monitors the health status of cells by surveilling fragments of foreign molecules from invaders presented on MHC I complexes at the cell surface. Here, the authors investigate the sequence of events of MHC I assembly and quality control cycle.
- Alexander Domnick
- , Christian Winter
- & Robert Tampé
Nature Communications 13, 4701
Research
10 August 2022 | Open Access

Predictive value of neutrophil-to-lymphocyte ratio for the fatality of COVID-19 patients complicated with cardiovascular diseases and/or risk factors
- Akinori Higaki
- , Hideki Okayama
- & Shingo Matsumoto
Scientific Reports 12, 13606
Research
10 August 2022 | Open Access

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection

Emerging SARS-CoV-2 Omicron sub-lineages BA.4 and BA.5 raise concerns about potential immune evasion. Here, Khan et al. show that both BA.4 and BA.5 are able to escape immune response induced by prior BA.1 infection, but that this effect is less pronounced in vaccinated individuals.
- Khadija Khan
- , Farina Karim
- & Alex Sigal
Nature Communications 13, 4686

All Research & Reviews

News and Comment

News & Views | 10 August 2022

Immune cells use hunger hormones to aid healing

Immune cells called monocytes have long been implicated in the killing of invading bacteria. However, a closer look reveals a surprising role for them: monocytes partner with a hormone to improve skin healing after bacterial infection.
- Vishwa Deep Dixit
Nature
News & Views | 10 August 2022

Neurons shape the identity of microglia in the brain

Microglia are immune cells that regulate the function and activity of the nervous system. Detailed molecular and spatial studies in mice reveal that different types of neuron govern the density and states of nearby microglia, interactions that can shape local neural circuits.

Nature
News | 10 August 2022

Will ‘Centaurus’ be the next global coronavirus variant? Indian cases offers clues

The BA.2.75 variant is rising fast in the country, but hospitalization rates are low so far.
- Ewen Callaway
Nature
Editorial | 09 August 2022

Preventive HIV drug shows urgent need for transparency on pricing

The drug cabotegravir could be a game-changer in the fight against HIV/AIDS — but we need to know why it costs so much.

Nature 608, 239
Research Highlights | 09 August 2022

Fungus hijacks TLR4 to build a type 2 immune niche

A fungal virulence factor promotes pathogenic type 2 immunity via Toll-like receptor 4.
- Yvonne Bordon
Nature Reviews Immunology, 1
Comments & Opinion | 09 August 2022

SARS-CoV-2 hybrid immunity: silver bullet or silver lining?

Hybrid immunity occurs in those who have been both infected with and vaccinated against SARS-CoV-2. But how well does such hybrid immunity protect against the virus and its emerging variants?
- Rahul Suryawanshi
- & Melanie Ott
Nature Reviews Immunology, 1-2

All News & Comment

Immunology

Featured

Immune cells use hunger hormones to aid healing

Neurons shape the identity of microglia in the brain

Inflammatory platelet death drives sepsis

Latest Research and Reviews

A monocyte–leptin–angiogenesis pathway critical for repair post-infection

The cross-talk of cancer-associated fibroblasts assist in prognosis and immunotherapy in patients with breast carcinoma

Diverse mutational landscapes in human lymphocytes

Molecular basis of MHC I quality control in the peptide loading complex

Predictive value of neutrophil-to-lymphocyte ratio for the fatality of COVID-19 patients complicated with cardiovascular diseases and/or risk factors

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection

News and Comment

Immune cells use hunger hormones to aid healing

Neurons shape the identity of microglia in the brain

Will ‘Centaurus’ be the next global coronavirus variant? Indian cases offers clues

Preventive HIV drug shows urgent need for transparency on pricing

Fungus hijacks TLR4 to build a type 2 immune niche

SARS-CoV-2 hybrid immunity: silver bullet or silver lining?

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