Gastrointestinal models

  • Article |

    The influence of stress relaxation of the extracellular matrix on the formation of intestinal organoids was investigated. It was shown that a stress-relaxing synthetic matrix promotes crypt budding through increased symmetry breaking and niche cell formation.

    • Antonius Chrisnandy
    • , Delphine Blondel
    •  & Matthias P. Lutolf