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Self-repair protects microtubules from destruction by molecular motors
Molecular motors destroy a microtubule lattice as they walk on it, but it is now shown that a self-healing process incorporates new dimers in the damaged regions and prevents microtubule disassembly.
- Sarah Triclin
- , Daisuke Inoue
- & Manuel Théry
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Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions
An approach to form protein-based hydrogels in living cells that resemble physiological hydrogel-like size-dependent molecular sieves is presented. Synthetic RNA granules mimics are obtained by functionalizing these entities with RNA-binding motifs.
- Hideki Nakamura
- , Albert A. Lee
- & Takanari Inoue