The genetics of autoimmune Addison disease: past, present and future

This Review discusses the current understanding of the genetics of Addison disease and outlines autoimmune mechanisms that could underlie effects on the adrenal cortex.

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  • Diabetes mellitus is a global health issue, yet huge regional disparities exist in its care, including in access to basic necessities such as insulin. In this Viewpoint, six experts from different regions discuss differences in access to insulin and other diabetes mellitus therapies as well as the key barriers in diabetes mellitus care accessibility and potential solutions.

    • Michael Fralick
    • Alicia J. Jenkins
    • Maria Inês Schmidt
    Viewpoint

  • Achondroplasia is the most common skeletal dysplasia and is characterized by various lifelong clinical, functional and psychosocial challenges for affected individuals. This first International Consensus Statement on the care of children and adults with achondroplasia aims to facilitate the global standardization and improvement of achondroplasia clinical care.

    • Ravi Savarirayan
    • Penny Ireland
    • Svein Otto Fredwall
    Consensus Statement

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