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  • At the recent Artificial Intelligence Applications in Biopharma Summit in Boston, USA, a panel of scientists from industry who work at the interface of machine learning and pharma discussed the diverging opinions on the past, present and future role of AI for ADME/Tox in drug discovery and development.

    • Barun Bhhatarai
    • W. Patrick Walters
    • Sean Ekins
    Comment
  • Rapid progress in machine learning is enabling opportunities for improved clinical decision support. Importantly, however, developing, validating and implementing machine learning models for healthcare entail some particular considerations to increase the chances of eventually improving patient care.

    • Po-Hsuan Cameron Chen
    • Yun Liu
    • Lily Peng
    Comment
  • The redefinition of SI units removes materiality from science’s weights and measures. There’s logic to the decision, but it reminds us what we still don’t know about nature’s scales.

    Editorial
  • Nian Sun, a professor at Northeastern University (Electrical and Computer Engineering Department), talks to Nature Materials about the potential applications of multiferroic materials, and issues associated with commercializing these technologies.

    • Stephen Shevlin
    Q&A
  • Much academic and industrial effort has been devoted to the study of multiferroics, but if related technologies are to have real-world impact, market awareness and reproducibility are also key.

    Editorial
  • Topological structures have considerable potential in nanoelectronics and new device concepts. They are key to the design and understanding of novel functionalities in ferroic materials — that is, materials that have one or more types of built-in order such as magnetic, ferroelectric, ferroelastic and multiferroic materials.

    • Jan Seidel
    Comment
  • As the periodic table reaches the age of 150, we reflect on the historical search for new elements, and consider element usage trends in some key research fields.

    Editorial
  • This Comment describes some of the common pitfalls encountered in deriving and validating predictive statistical models from high-dimensional data. It offers a fresh perspective on some key statistical issues, providing some guidelines to avoid pitfalls, and to help unfamiliar readers better assess the reliability and significance of their results.

    • Andrew E. Teschendorff
    Comment
  • There is room for improvement in materials sustainability, provided we examine carefully the whole value chain.

    Editorial
  • Emily Mayhew, a historian within the Department of Bioengineering at Imperial College London, talks to Nature Materials about the advances that have been made in medicine and, in particular, prosthetics since World War I.

    • Amos Matsiko
    Q&A
  • Prostheses today can trace their roots to the rudimentary designs of the First World War, but since then there have been significant advances that have improved the quality of life of amputees.

    Editorial
  • Highly sophisticated materials properties and engineering efforts are crucial for the success of missions for space exploration and settlement.

    Editorial
  • Space missions require materials that can preserve functional integrity under extreme conditions of heat, impact and radiation. This Comment outlines the materials properties needed for some of the most ambitious space missions and presents the design and testing principles before their incorporation.

    • Tommaso Ghidini
    Comment
  • Treating living matter as a material has immense biomedical potential, but it’s worth acknowledging how the notion unsettles longstanding preconceptions and raises challenging new questions.

    Editorial
  • Lessons learnt from Horizon 2020 and a determination to become a world-class hub for entrepreneurship form the basis of the European Commission’s ambitious Research and Innovation budget.

    Editorial