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  • Mechanical confinement of fibroblasts into micrometre-sized channels deforms the cell nucleus, leading to temporary nuclear lamina destablization and disassembly, loss of lamina-associated domains in chromatin and a decrease in histone and DNA methylation. These mechanically induced alterations in chromatin boost the conversion of fibroblasts into neurons and pluripotent stem cells and thus can be explored for cell engineering applications.

    • Yang Song
    • Jennifer Soto
    • Song Li
  • Two-dimensional materials can present ferroelectricity by layer sliding, but electrical confirmation is lacking due to narrow bandgaps. Here, a single-crystal coordination polymer with large bandgap enabling direct electrical measurement of PE hysteresis is shown to present sliding ferroelectricity.

    • Le-Ping Miao
    • Ning Ding
    • Yi Zhang
  • Solid-state ionic conduction is a key enabler of electrochemical energy storage and conversion. A quantitative framework for ionic conduction between atomistic and macroscopic timescales in β- and β″-aluminas is now proposed for ‘atoms-to-device’ multiscale modelling and optimization.

    • Andrey D. Poletayev
    • James A. Dawson
    • Aaron M. Lindenberg
  • Heterostructures combine the unique properties of each constituent, improving the efficiency and stability of perovskite-based optoelectronic devices, yet the films suffer from poor compositional and structural uniformity. Here, the authors demonstrate a ligand-assisted welding process to fabricate a series of epitaxial 2D and 3D perovskite heterostructures.

    • Zhaohua Zhu
    • Chao Zhu
    • Wei Huang
  • Knowledge of band structure aids in understanding charge transport behaviour, yet it has proved impossible to measure the conduction (LUMO) band of organic semiconductors, in particular due to sample degradation by the electron beam. To address this, the authors developed and used AR-LEIPS to reveal the LUMO band dispersion of pentacene.

    • Haruki Sato
    • Syed A. Abd. Rahman
    • Hiroyuki Yoshida
  • Single-molecule electronics provide the potential solution for high-density integration and low-power consumption in massive data-driven applications, but have yet to be explored. Here, the authors report low-power logic-in-memory operations, based on single electric dipole flipping in the two-terminal single-metallofullerene device at room temperature.

    • Jing Li
    • Songjun Hou
    • Wenjing Hong
  • Colour centre emission from hexagonal boron nitride (hBN) holds promise for quantum technologies but activation and tuning are challenging. Here, the authors show twist-angle emission brightness tuning and external voltage brightness modulation at the twisted interface of hBN flakes.

    • Cong Su
    • Fang Zhang
    • Alex Zettl
  • Directed cell movement known as durotaxis, typically associated with cellular migration in response to a substrate gradient of increasing stiffness, is now shown to also occur in the opposite direction, following a gradient of decreasing stiffness.

    • Aleksi Isomursu
    • Keun-Young Park
    • David J. Odde
  • Superconductivity is reported in magic-angle twisted four-layer and five-layer graphene systems. While they find that all magic-angle graphene systems fit into a unified hierarchy of systems that share a set of flat bands in their electronic band structures, they also report that there is a key distinction between magic-angle twisted bilayer graphene and the other family members, related to the difference in the way the electrons move between the layers in a magnetic field.

    • Jeong Min Park
    • Yuan Cao
    • Pablo Jarillo-Herrero
  • The partial oxidation of CH4 to CH3OH is challenging to perform in artificial systems due to ready over-oxidation to CO and CO2. Here by confining mono-iron hydroxyl sites in a metal–organic framework, photo-oxidation of CH4 to CH3OH is achieved with high selectivity and time yield.

    • Bing An
    • Zhe Li
    • Martin Schröder
  • Here the authors describe a method for remote magnetothermal stimulation of neurons that achieves subsecond behavioural responses in Drosophila fruit flies by combining magnetic nanoparticles with TRPA1-A, a rate-sensitive thermoreceptor. Tuning the properties of magnetic nanoparticles to respond to different magnetic field strengths and frequencies enables multichannel thermal magnetogenetic stimulation.

    • Charles Sebesta
    • Daniel Torres Hinojosa
    • Jacob T. Robinson
  • Hafnium dioxide is of technological interest as it is compatible with silicon; however, previous work indicates that a nanometre grain size is required to generate ferroelectricity. Here ferroelectric Y-doped HfO2 thin films with high crystallinity are grown with large crystal grain sizes, indicating that ferroelectricity is intrinsic.

    • Yu Yun
    • Pratyush Buragohain
    • Xiaoshan Xu