Research articles

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  • Detailed structural analysis of Palaeospondylus gunni from the Middle Devonian period shows strong resemblance to Eusthenopteron and Panderichthys, indicating that it was a sarcopterygian and most probably a stem-tetrapod.

    • Tatsuya Hirasawa
    • Yuzhi Hu
    • Shigeru Kuratani
    Article
  • Two remarkably large sites in southwest Amazonia, belonging to the Casarabe culture, include complex civic-ceremonial architecture and large water-management infrastructure, representing a type of tropical low-density urbanism that has not previously been described in Amazonia.

    • Heiko Prümers
    • Carla Jaimes Betancourt
    • Martin Schaich
    Article Open Access
  • A small molecule can bypass the RNA-editing enzyme ADAR1 to directly activate the Z-form nucleic acid sensor ZBP1, induce necroptosis in tumour fibroblasts and reverse resistance to immune checkpoint blockade in mouse models of melanoma.

    • Ting Zhang
    • Chaoran Yin
    • Siddharth Balachandran
    Article
  • Longitudinal imaging of nerve fibres in mice reveals that reinnervation after nerve injury can lead to neuropathic pain, which is mediated through aberrant patterns of reinnervation in denervated areas by nociceptors.

    • Vijayan Gangadharan
    • Hongwei Zheng
    • Rohini Kuner
    Article Open Access
  • A quantum network formed by three optically connected nodes comprising solid-state qubits demonstrates the teleportation of quantum information between two non-neighbouring nodes, negating the need for a direct connection between them.

    • S. L. N. Hermans
    • M. Pompili
    • R. Hanson
    Article Open Access
  • Using a compact, particle-beam-driven plasma-based accelerator to accelerate high-quality electron beams that are completely characterized in the six-dimensional phase space, free-electron lasing  is observed with narrow-band amplified radiation in the infrared range.

    • R. Pompili
    • D. Alesini
    • M. Ferrario
    Article
  • Molecular analyses of modern and fossil skeletal samples reveal that elevated metabolic rates consistent with endothermy evolved independently in mammals and plesiosaurs, and ornithodirans: Exceptional metabolic rates are ancestral to dinosaurs and pterosaurs and were acquired before energetically costly adaptations, such as flight.

    • Jasmina Wiemann
    • Iris Menéndez
    • Derek E. G. Briggs
    Article
  • A computational system termed MetaWIBELE (workflow to identify novel bioactive elements in the microbiome) is used to identify microbial gene products that are potentially bioactive and have a functional role in the pathogenesis of inflammatory bowel disease.

    • Yancong Zhang
    • Amrisha Bhosle
    • Eric A. Franzosa
    Article
  • A study of zebrafish identifies an innate mechanism of blood vessel formation through the transdifferentiation of lymphatic endothelial cells, and provides in vivo evidence for a link between cell ontogeny and functionality in endothelial cells.

    • Rudra N. Das
    • Yaara Tevet
    • Karina Yaniv
    Article
  • Electrically controlled quantum confinement of excitons to below 10 nm is achieved in a 2D semiconductor by combining in-plane electric fields with interactions between excitons and free charges.

    • Deepankur Thureja
    • Atac Imamoglu
    • Puneet A. Murthy
    Article
  • By using 17 physical qubits in a superconducting circuit to encode quantum information in a surface-code logical qubit, fast (1.1 μs) and high-performance (logical error probability of 3%) quantum error-correction cycles are demonstrated.

    • Sebastian Krinner
    • Nathan Lacroix
    • Andreas Wallraff
    Article
  • A molecular mechanism involving CCR5 and CCL5 determines the temporal window in which a memory can be linked with subsequent memories, and in aged mice an increase in CCR5 is associated with defects in memory linking.

    • Yang Shen
    • Miou Zhou
    • Alcino J. Silva
    Article