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FLOW CHEMISTRY

Let’s stick together for continuous flow biocatalysis

Fusion systems have been designed that link enzymes to cofactors and immobilization modules through appropriate synthetic spacers. These modular biocatalysts (assembling catalysis, cofactor provision/regeneration and assisted immobilization) are suited to heterogeneous biocatalysis systems and can be efficiently used in continuous flow reactors.

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Fig. 1: Fusion system for cofactor-dependent continuous flow biocatalysis.

References

  1. 1.

    Tamborini, L. et al. Trends Biotechnol. 36, 73–88 (2018).

    CAS  Article  Google Scholar 

  2. 2.

    Contente, M. L. et al. Green Chem. 21, 3263–3266 (2019).

    CAS  Article  Google Scholar 

  3. 3.

    Dall’Oglio, F. et al. Catal. Commun. 93, 29–32 (2017).

    Article  Google Scholar 

  4. 4.

    Velasco‐Lozano, S. et al. Angew. Chem. Int. Ed. 16, 771–775 (2017).

    Article  Google Scholar 

  5. 5.

    Benítez-Mateos, A. I. et al. ACS Sustain. Chem. Eng. 6, 13151–13159 (2018).

    Article  Google Scholar 

  6. 6.

    Fu, J. et al. Nat. Nanotechnol. 9, 531–536 (2014).

    CAS  Article  Google Scholar 

  7. 7.

    Hartley, C. J. et al. Nat. Catal. https://doi.org/10.1038/s41929-019-0353-0 (2019).

  8. 8.

    Aalbers, F. S. & Fraaije, M. W. ChemBioChem 20, 20–28 (2019).

    CAS  Article  Google Scholar 

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Correspondence to Francesco Molinari.

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Contente, M.L., Molinari, F. Let’s stick together for continuous flow biocatalysis. Nat Catal 2, 951–952 (2019). https://doi.org/10.1038/s41929-019-0363-y

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