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Single-molecule FRET on its way to structural biology in live cells

Single-molecule FRET is making stepwise progress toward the realization of its full potential: becoming the reference technique to monitor protein structural dynamics in live cells.

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Fig. 1: Toward distance and dynamic measurements in living cells using smFRET.


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Correspondence to Emmanuel Margeat.

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Quast, R.B., Margeat, E. Single-molecule FRET on its way to structural biology in live cells. Nat Methods 18, 344–345 (2021).

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