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Handling heme with care

Heme-containing proteins support a broad range of cellular functions. A new crystal structure explains how an integral-membrane heme lyase attaches the hydrophobic heme to soluble proteins.

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Fig. 1: A heme handoff during cytochrome maturation by system I.


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Correspondence to Breann L. Brown or T. M. Iverson.

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Brown, B.L., Iverson, T.M. Handling heme with care. Nat Chem Biol 17, 751–752 (2021).

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