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Understanding the language of drugged plants

Plant biologists have recognized the potential in using small molecules identified from chemical libraries to provide insights into biological questions relevant to plants. However, the classical genetics mindset still predominant among plant scientists should evolve to embrace cross-disciplinary chemical genetics projects that will benefit future plant research.

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Fig. 1: Balance between classical genetics and chemical genetics for probing mechanisms in plant biology.
Fig. 2: Conventional and current trends in plant chemical genetics.
Fig. 3: Plant chemical genetics will benefit from cross-disciplinary approaches.


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We thank N. Raikhel, G.R. Hicks, T. Beeckman, M. Kaiser, D. Audenaert, W. Dejonghe and K. Mishev for critical reading and valuable suggestions, and M. De Cock for help in preparing the manuscript. This work was supported by the Research Foundation-Flanders (project 3G009018 to E.R.).

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Correspondence to Eugenia Russinova.

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Halder, V., Russinova, E. Understanding the language of drugged plants. Nat Chem Biol 15, 1025–1028 (2019).

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