Extended Data Fig. 4: Comparison of ACSL structure in 17-mer bound to BuMiaB with that of full-length tRNAPhe bound to TmMiaA. | Nature

Extended Data Fig. 4: Comparison of ACSL structure in 17-mer bound to BuMiaB with that of full-length tRNAPhe bound to TmMiaA.

From: Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB

Extended Data Fig. 4

a, Cartoon overlay of the 13-mer (purple colour) and 17-mer (nucleotides 27-43) (green colour) structures in complex with BuMiaB plus 5’-dAH+Met (13-mer) or BuMiaB with SAM (17-mer), with that of Tm tRNAPhe in complex with MiaA (tan colour) (PDB ID: 2ZM5). b, Schematic diagram of the H-bonds formed between the 17-mer and BuMiaB.

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