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MICs (mg/L) of comparator β-lactams, Compound 2 and ETX0462 versus PAO1ΔampCΔpoxB, a P. aeruginosa lab strain devoid of intrinsic β-lactamase activity, as compared to an isogenic panel of derivative strains, each of which individually overexpresses a single β-lactamase. Greater than two-dilution changes are considered phenotypically significant. Values shown are the mode of 3 biological replicates.