Extended Data Fig. 8: Effects of H9T on human CD4+ T cells. | Nature

Extended Data Fig. 8: Effects of H9T on human CD4+ T cells.

From: An engineered IL-2 partial agonist promotes CD8+ T cell stemness

Extended Data Fig. 8

ad, Phenotypic analysis of expanded human CD4+ T cells. Pre-activated human CD4+ cells were cultured with 10 nM H9T, IL-2, IL-15, or IL-7 + IL-15 for 6 days, and mitochondrial membrane potential (a) and surface expression of TIM-3 (b), CCR7(c), and CD27 (d) were examined by flow cytometry analysis after staining. Data are presented as mean values ± SEM, n = 5 donors, with paired two-sided t-test. Data are representative of two independent experiments

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