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Zebrafish prrx1a mutants have normal hearts

Matters Arising to this article was published on 23 September 2020

The Original Article was published on 07 September 2017

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Fig. 1: Cardiac laterality in prrx1a-mutant embryos.
Fig. 2: Induction of off-target laterality phenotypes by injection of prrx1a-MO1.

Data availability

All data are available within the manuscript and its associated files. Source data are provided with this paper.


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We acknowledge support from the Dutch Heart Foundation grant CVON2014-18 CONCOR-GENES to J.B. and the National Institute of Health grants NIH R35 DE027550 to J.G.C., NIH R00 DE024190 to J.T.N. (National Institute of Dental and Craniofacial Research, NIDCR) and NIH R00 DE026239 to L.B. (NIDCR).

Author information




F.T.: project conception, experimental work, data analysis, manuscript writing; D.E.M.d.B.: project conception, experimental work; L.B.: experimental work, data analysis, manuscript revision; N.N.: experimental work, data analysis; H.A.A.: experimental work, data analysis; S.W.: experimental work; J.T.N.: zebrafish lines, manuscript revision; J.G.C.: zebrafish lines, project conception, manuscript writing; J.B.: project conception, manuscript writing.

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Correspondence to J. Gage Crump or Jeroen Bakkers.

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Tessadori, F., de Bakker, D.E.M., Barske, L. et al. Zebrafish prrx1a mutants have normal hearts. Nature 585, E14–E16 (2020).

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