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EPIDEMIOLOGY

When specialized clones go global

Multi-drug resistant Mycobacterium abscessus clones from individuals who smoke have infiltrated the narrow niche of patients with cystic fibrosis, which has resulted in surprising specialization and subsequent worldwide dissemination.

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Fig. 1: Large-scale adaptive jumps versus local fine-tuning of human pathogens.

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Correspondence to Thierry Wirth.

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Wirth, T. When specialized clones go global. Nat Microbiol 6, 1215–1216 (2021). https://doi.org/10.1038/s41564-021-00967-z

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