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Muscle on demand

Light-activated protein actuators composed of bioengineered motors and molecular scaffolds achieve millimetre-scale mechanical work, which holds promise for microrobotics applications.

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Fig. 1: Pliers closing with active protein networks.
Fig. 2: Motor abundance varies inversely with size and increases as technology progresses.


  1. Burridge, K. & Wittchen, E. S. J. Cell. Biol. 200, 9–19 (2013).

    CAS  Article  Google Scholar 

  2. Nitta, T., Wang, Y., Du, Z., Morishima, K. & Hiratsuka, Y. Nat. Mater. (2021).

  3. Baughman, R. H. et al. Science 284, 1340–1344 (1999).

    CAS  Article  Google Scholar 

  4. Haines, C. S. et al. Science 343, 868–872 (2014).

    CAS  Article  Google Scholar 

  5. Dattler, D. et al. Chem. Rev. 120, 310–433 (2019).

    Article  Google Scholar 

  6. Needleman, D. & Dogic, Z. Nat. Rev. Mater. 2, 17048 (2017).

    CAS  Article  Google Scholar 

  7. Nakamura, M. et al. Nat. Nanotechnol. 9, 693–697 (2014).

    CAS  Article  Google Scholar 

  8. Fennimore, A. M. et al. Nature 424, 408–410 (2003).

    CAS  Article  Google Scholar 

  9. Burgert, I. & Fratzl, P. Philos. Trans. A Math. Phys. Eng. Sci. 367, 1541–1557 (2009).

    CAS  Google Scholar 

  10. Armstrong, M. J. & Hess, H. ACS Nano 8, 4070–4073 (2014).

    CAS  Article  Google Scholar 

Download references

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Correspondence to Henry Hess.

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Hess, H. Muscle on demand. Nat. Mater. 20, 1040–1041 (2021).

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