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Epigenetic regulation of mechanotransduction

The DNA methylation of the promoter region of the oncogenic Yes-associated protein is reversibly regulated by the stiffness of the extracellular matrix.

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Fig. 1: Mechanisms of mechanotransduction and the role of the epigenome.


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Correspondence to Ryan Stowers or Ovijit Chaudhuri.

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Stowers, R., Chaudhuri, O. Epigenetic regulation of mechanotransduction. Nat Biomed Eng 5, 8–10 (2021).

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