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Gastric bypass bariatric surgery in patients undergoing allogeneic hematopoietic stem cell transplantation warrants special considerations

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Fig. 1: aGVHD in bariatric surgery patients.

References

  1. Weiss BM, Vogl DT, Berger NA, Stadtmauer EA, Lazarus HM. Trimming the fat: obesity and hematopoietic cell transplantation. Bone Marrow Transplant. 2013;48:1152–60. https://doi.org/10.1038/bmt.2012.201.

    CAS  Article  PubMed  Google Scholar 

  2. Navarro WH, Agovi MA, Logan BR, Ballen K, Bolwell BJ, Frangoul H, et al. Obesity does not preclude safe and effective myeloablative hematopoietic cell transplantation (HCT) for acute myelogenous leukemia (AML) in adults. Biol Blood Marrow Transplant. 2010;16:1442–50. https://doi.org/10.1016/j.bbmt.2010.04.009.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Nikolousis E, Nagra S, Paneesha S, Delgado J, Holder K, Bratby L, et al. Allogeneic transplant outcomes are not affected by body mass index (BMI) in patients with haematological malignancies. Ann Hematol. 2010;89:1141–5. https://doi.org/10.1007/s00277-010-1001-6.

    Article  PubMed  Google Scholar 

  4. Fleming DR, Rayens MK, Garrison J. Impact of obesity on allogeneic stem cell transplant patients: a matched case-controlled study. Am J Med. 1997;102:265–8. https://doi.org/10.1016/S0002-9343(96)00450-0.

    CAS  Article  PubMed  Google Scholar 

  5. Przepiorka D, Weisdorf D, Martin P, Klingemann HG, Beatty P, Hows J, et al. 1994 consensus conference on acute GVHD grading. Bone Marrow Transplant. 1995;15:825–8.

    CAS  PubMed  Google Scholar 

  6. Arora M, Klein JP, Weisdorf DJ, Hassebroek A, Flowers ME, Cutler CS, et al. Chronic GVHD risk score: a Center for International Blood and Marrow Transplant Research analysis. Blood. 2011;117:6714–20. https://doi.org/10.1182/blood-2010-12-323824.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  7. Muscaritoli M, Grieco G, Capria S, Iori AP, Rossi Fanelli F. Nutritional and metabolic support in patients undergoing bone marrow transplantation. Am J Clin Nutr. 2002;75:183–90. https://doi.org/10.1093/ajcn/75.2.183.

    CAS  Article  PubMed  Google Scholar 

  8. Rogers CC, Alloway RR, Alexander JW, Cardi M, Trofe J, Vinks AA. Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study. Clin Transplant. 2008;22:281–91. https://doi.org/10.1111/j.1399-0012.2007.00783.x.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes. 2010;59:3049–57. https://doi.org/10.2337/db10-0253.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

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Gergis, U., Reich-Slotky, R. & Abdulahad, B. Gastric bypass bariatric surgery in patients undergoing allogeneic hematopoietic stem cell transplantation warrants special considerations. Bone Marrow Transplant 55, 2202–2203 (2020). https://doi.org/10.1038/s41409-020-0922-5

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