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Management of hypertensive disorders of late pregnancy

New data from a randomized controlled trial suggest that a strategy of expectant monitoring aimed at prolonging pregnancy until 37 weeks of gestation might be preferable to immediate delivery in women with nonsevere hypertensive disorders of late pregnancy. In this study, which included 703 women, the composite incidence of adverse maternal outcomes (including thromboembolic disease and eclampsia) did not differ significantly between the expectant monitoring and immediate delivery groups (3.1% versus 1.1%), whereas the incidence of neonatal respiratory distress syndrome was significantly higher in the immediate delivery group (5.7% versus 1.7%).


  1. Broekhuijsen, K. et al. Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial. Lancet 10.1016/S0140-6736(14)61998-X

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Management of hypertensive disorders of late pregnancy. Nat Rev Nephrol 11, 316 (2015).

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