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Helicobacter pylori

Helicobacter pylori gastritis—a novel distinct disease entity

A global consensus report on Helicobacter pylori gastritis has been developed. Topics discussed include whether dyspepsia caused by H. pylori infection is separate from functional dyspepsia or not, the evaluation method for H. pylori-induced gastritis, eradication therapy for H. pylori gastritis to prevent gastric carcinogenesis and management after H. pylori eradication.

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Figure 1: Major findings from the Kyoto Global Consensus Meeting on Helicobacter pylori gastritis.

References

  1. Sugano, K., Tack, J., Kuipers, E. J., Graham, D. Y. & El-Omar, E. M. Kyoto global consensus report on Helicobacter pylori gastritis. Gut 64, 1353–1367 (2015).

    Article  Google Scholar 

  2. Tack. et al. Functional gastroduodenal disorders. In ROME III: the Functional Gastrointestinal Disorders (ed. Drossman, D. A.). 419–486 (Degnon Associates, 2006).

    Google Scholar 

  3. Tack, J. et al. Functional gastroduodenal disorders. Gastroenterology 130, 1466–1479 (2006).

    Article  Google Scholar 

  4. Suzuki, H., Nishizawa, T. & Hibi, T. Can Helicobacter pylori-associated dyspepsia be categorized as functional dyspepsia? J. Gastroenterol. Hepatol. 26 (Suppl. 3), 42–45 (2011).

    Article  Google Scholar 

  5. Suzuki, H. & Moayyedi, P. Helicobacter pylori infection in functional dyspepsia. Nat. Rev. Gastroenterol. Hepatol. 10, 168–174 (2013).

    Article  Google Scholar 

  6. Zhao B. et al. Efficacy of Helicobacter pylori eradication therapy on functional dyspepsia: a meta-analysis of randomized controlled studies with 12-month follow-up. J. Clin. Gastroenterol. 48, 241–247 (2014).

    CAS  Article  Google Scholar 

  7. Saito, Y. et al. Dysfunctional gastric emptying with down-regulation of muscle-specific microRNAs in Helicobacter pylori-infected mice. Gastroenterology 140, 189–198 (2011).

    CAS  Article  Google Scholar 

  8. Saka, A., Yagi, K. & Nimura, S. OLGA- and OLGIM-based staging of gastritis using narrow-band imaging magnifying endoscopy. Dig. Endosc. http://dx.doi.org/10.1111/den.12483.

  9. Dixon, M. F., Genta, R. M., Yardley, J. H. & Correa, P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am. J. Surg. Pathol. 20, 1161–1181 (1996).

    CAS  Article  Google Scholar 

  10. Sugano, K. Should we still subcategorize Helicobacter pylori-associated dyspepsia as functional disease? J. Neurogastroenterol. Motil. 17, 366–371 (2011).

    Article  Google Scholar 

Download references

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Correspondence to Hidekazu Suzuki.

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Competing interests

During the past 2 years, H.S. has received scholarship funds for research from Astellas, Astra-Zeneca, Otsuka Pharmaceutical, Takeda Pharmaceutical and Zeria Pharmaceutical. and received service honouraria from Astellas, Astra-Zeneca, Otsuka Pharmaceutical, Takeda Pharmaceutical and Zeria Pharmaceutical. H.S. attended the Kyoto global consensus meeting as one of collaborators, but was not directly involved in writing the report. H.M. declares no competing interests.

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Suzuki, H., Mori, H. Helicobacter pylori gastritis—a novel distinct disease entity. Nat Rev Gastroenterol Hepatol 12, 556–557 (2015). https://doi.org/10.1038/nrgastro.2015.158

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